IL-2 regulates SEB induced toxic shock syndrome in BALB/c mice.
BACKGROUND:Toxic Shock Syndrome (TSS) is characterized by fever, rash, hypotension, constitutional symptoms, and multi-organ involvement and is caused by Staphylococcus aureus enterotoxins such as Staphylococcal Enterotoxin B (SEB).SEB binds to the MHC-IIalpha chain and is recognized by the TCRbeta Microphone chain of the Vbeta8 TCR(+) T cells.The